| Protein name |
Truffle sweet protein |
| Host compatibility |
Komagatella phaffi (Pichia pastoris) |
| Yield |
Proprietary info of Mycotechnology |
| Scale (in specific example) |
Pilot scale (McFarland et al., 2024)
|
| Biggest scale product has been develloped in this organism |
Pilot scale (McFarland et al., 2024)
|
| Regulatory status in Europe |
Not allowed |
| Regulatory status in other parts of the world |
No FDA GRAS approval in US, not allowed in Canada. Mycotechnology has self-affirmed GRAS
|
| Companies producing this protein in this organism |
Mycotechnology
|
| Extra/remark |
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| Publications/references |
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Nadal, M., Clark, A. J., Guo, Z., Gravina, S. A., Westgate, A., Alkotaini, B., Han, A., Sharkey, B., Strassburger, E., Meilen, J., Chang, H., & Inc, M. (2021, December). US11297861B2 - Sweet protein from truffle - Google Patents. https://patents.google.com/patent/US11297861B2/en
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McFarland, C., Alkotaini, B., Cowen, C. P., Edwards, M. G., Grein, E., Hahn, A. D., Jennings, J. C., Patnaik, R., Potter, S. M., Rael, L. T., Sharkey, B. P., Taylor, S. L., Totman, R., Van Simaeys, K., Vo, P., Zhao, D., & Connors, D. E. (2024). Discovery, Expression, and In Silico Safety Evaluation of Honey Truffle Sweetener, a Sweet Protein Derived from Mattirolomyces terfezioides and Produced by Heterologous Expression in Komagataella phaffii. Journal of Agricultural and Food Chemistry, 72(35), 19470–19479. https://doi.org/10.1021/acs.jafc.4c04368
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Mycotechnology. (n.d.). Honey Truffle Sweet Protein - MycoTechnology. Retrieved September 3, 2025, from https://www.mycoiq.com/ingredients/honey-truffle-sweet-protein/
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